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Genome instability of ageing stem cells—Induction and defence mechanisms
The mammalian organism is comprised of tissue types with varying degrees of self-renewal and regenerative capacity. In most organs self-renewing tissue-specific stem and progenitor cells contribute to organ maintenance, and it is vital to maintain a functional stem cell pool to preserve organ homeos...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504031/ https://www.ncbi.nlm.nih.gov/pubmed/25668152 http://dx.doi.org/10.1016/j.arr.2015.01.004 |