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Integrated sequence and expression analysis of ovarian cancer structural variants underscores the importance of gene fusion regulation
BACKGROUND: Genomic rearrangements or structural variants (SVs) are one of the most common classes of mutations in cancer. METHODS: An integrated DNA sequencing and transcriptional profiling (RNA sequence and microarray gene expression data) analysis was performed on six ovarian cancer patient sampl...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504069/ https://www.ncbi.nlm.nih.gov/pubmed/26177635 http://dx.doi.org/10.1186/s12920-015-0118-9 |