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Integrated sequence and expression analysis of ovarian cancer structural variants underscores the importance of gene fusion regulation

BACKGROUND: Genomic rearrangements or structural variants (SVs) are one of the most common classes of mutations in cancer. METHODS: An integrated DNA sequencing and transcriptional profiling (RNA sequence and microarray gene expression data) analysis was performed on six ovarian cancer patient sampl...

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Detalles Bibliográficos
Autores principales: Mittal, Vinay K., McDonald, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504069/
https://www.ncbi.nlm.nih.gov/pubmed/26177635
http://dx.doi.org/10.1186/s12920-015-0118-9