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The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo

BACKGROUND: Combination therapy is a key strategy for minimizing drug resistance, a common problem in cancer therapy. The microtubule-depolymerizing agent vincristine is widely used in the treatment of acute leukemia. In order to decrease toxicity and chemoresistance of vincristine, this study will...

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Detalles Bibliográficos
Autores principales: Chao, Min-Wu, Lai, Mei-Jung, Liou, Jing-Ping, Chang, Ya-Ling, Wang, Jing-Chi, Pan, Shiow-Lin, Teng, Che-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504084/
https://www.ncbi.nlm.nih.gov/pubmed/26156322
http://dx.doi.org/10.1186/s13045-015-0176-7