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The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo
BACKGROUND: Combination therapy is a key strategy for minimizing drug resistance, a common problem in cancer therapy. The microtubule-depolymerizing agent vincristine is widely used in the treatment of acute leukemia. In order to decrease toxicity and chemoresistance of vincristine, this study will...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504084/ https://www.ncbi.nlm.nih.gov/pubmed/26156322 http://dx.doi.org/10.1186/s13045-015-0176-7 |