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Histone deacetylase inhibition sensitizes osteosarcoma to heavy ion radiotherapy

BACKGROUND: Minimal improvements in treatment or survival of patients with osteosarcoma have been achieved during the last three decades. Especially in the case of incomplete tumor resection, prognosis remains poor. Heavy ion radiotherapy (HIT) and modern anticancer drugs like histone deacetylase in...

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Detalles Bibliográficos
Autores principales: Blattmann, Claudia, Oertel, Susanne, Thiemann, Markus, Dittmar, Anne, Roth, Eva, Kulozik, Andreas E., Ehemann, Volker, Weichert, Wilko, Huber, Peter E., Stenzinger, Albrecht, Debus, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504102/
https://www.ncbi.nlm.nih.gov/pubmed/26178881
http://dx.doi.org/10.1186/s13014-015-0455-z