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Methylation Profiling of Multiple Tumor Suppressor Genes in Hepatocellular Carcinoma and the Epigenetic Mechanism of 3OST2 Regulation

DNA methylation is considered as a significant mechanism that silences tumor suppressor genes (TSGs) and could be used in the early diagnosis of cancer. Histone modifications often work together with DNA methylation; however, how these epigenetic alterations regulate TSGs remains unclear. Here, we d...

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Detalles Bibliográficos
Autores principales: Chen, Haiyan, Zhang, Tingguo, Sheng, Yan, Zhang, Cheng, Peng, Yunfei, Wang, Xiao, Zhang, Cuijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504110/
https://www.ncbi.nlm.nih.gov/pubmed/26185536
http://dx.doi.org/10.7150/jca.11691