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Human Stromal Cells in the Peripheral Zone of the Prostate Promote Tumorigenesis of Prostatic Cancer Stem Cells through Up-regulation of C-Kit Expression

Objective: Most prostate cancers originate from the prostatic peripheral zone (PZ). We tested the hypothesis that the stromal cells from PZ and transitional zone (TZ) have differential effects on the ability of tumorigenesis. Methods: Stromal cells isolated from the PZ and TZ of normal human prostat...

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Detalles Bibliográficos
Autores principales: Peng, Yubing, Chen, Qi, Gu, Meng, Chen, Yanbo, Zhang, Ming, Zhou, Juan, Wang, Hao, Gao, Yan, Li, Wenji, Wang, Zhong, Cai, Zhikang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504114/
https://www.ncbi.nlm.nih.gov/pubmed/26185540
http://dx.doi.org/10.7150/jca.9961