Could the Anti-Chaperone VER155008 Replace Temozolomide for Glioma Treatment

Cancer inducible molecular chaperone HSP90 is of great importance as an anticancer target. Proteomic analysis showed that inhibiting HSP90 by the geldanamycin derivative, 17-AAG elevated the expression of the co-chaperone Hsp70. In this study we used HSP90 selective inhibitor 17-AAG and HSP70/90 dua...

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Detalles Bibliográficos
Autores principales: Shervington, Leroy, Patil, Harshada, Shervington, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504115/
https://www.ncbi.nlm.nih.gov/pubmed/26185541
http://dx.doi.org/10.7150/jca.12251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504115/
https://www.ncbi.nlm.nih.gov/pubmed/26185541
http://dx.doi.org/10.7150/jca.12251

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