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Systems biology surveillance decrypts pathological transcriptome remodeling

BACKGROUND: Pathological cardiac development is precipitated by dysregulation of calreticulin, an endoplasmic reticulum (ER)-resident calcium binding chaperone and critical contributor to cardiogenesis and embryonic viability. However, pleiotropic phenotype derangements induced by calreticulin defic...

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Detalles Bibliográficos
Autores principales: Faustino, Randolph S., Wyles, Saranya P., Groenendyk, Jody, Michalak, Marek, Terzic, Andre, Perez-Terzic, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504166/
https://www.ncbi.nlm.nih.gov/pubmed/26179794
http://dx.doi.org/10.1186/s12918-015-0177-8