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Systems biology surveillance decrypts pathological transcriptome remodeling
BACKGROUND: Pathological cardiac development is precipitated by dysregulation of calreticulin, an endoplasmic reticulum (ER)-resident calcium binding chaperone and critical contributor to cardiogenesis and embryonic viability. However, pleiotropic phenotype derangements induced by calreticulin defic...
Autores principales: | Faustino, Randolph S., Wyles, Saranya P., Groenendyk, Jody, Michalak, Marek, Terzic, Andre, Perez-Terzic, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504166/ https://www.ncbi.nlm.nih.gov/pubmed/26179794 http://dx.doi.org/10.1186/s12918-015-0177-8 |
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