BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene

BACKGROUND: Chronic Myeloid Leukaemia (CML) is caused by the BCR/ABL1 fusion gene. Both the presence and the levels of BCR/ABL1 expression seem to be critical for CML progression from chronic phase (CP) to blast crisis (BC). After the oncogenic translocation, the BCR/ABL1 gene is under the transcrip...

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Detalles Bibliográficos
Autores principales: Sharma, Nitesh, Magistroni, Vera, Piazza, Rocco, Citterio, Stefania, Mezzatesta, Caterina, Khandelwal, Praveen, Pirola, Alessandra, Gambacorti-Passerini, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504180/
https://www.ncbi.nlm.nih.gov/pubmed/26179066
http://dx.doi.org/10.1186/s12943-015-0407-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504180/
https://www.ncbi.nlm.nih.gov/pubmed/26179066
http://dx.doi.org/10.1186/s12943-015-0407-0

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