Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

BACKGROUND: Although Imatinib mesylate has revolutionized the treatment of chronic myeloid leukemia, some patients develop resistance with progression of leukemia. Alternative or additional targeting of signalling pathways deregulated in Bcr-Abl-driven chronic myeloid leukemia may provide a feasible...

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Detalles Bibliográficos
Autores principales: Troadec, Samuel, Blairvacq, Mélina, Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Berthou, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504225/
https://www.ncbi.nlm.nih.gov/pubmed/26184865
http://dx.doi.org/10.1186/s12929-015-0163-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504225/
https://www.ncbi.nlm.nih.gov/pubmed/26184865
http://dx.doi.org/10.1186/s12929-015-0163-x

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