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Antitumoral effects of cyclin-dependent kinases inhibitors CR8 and MR4 on chronic myeloid leukemia cell lines

BACKGROUND: Although Imatinib mesylate has revolutionized the treatment of chronic myeloid leukemia, some patients develop resistance with progression of leukemia. Alternative or additional targeting of signalling pathways deregulated in Bcr-Abl-driven chronic myeloid leukemia may provide a feasible...

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Detalles Bibliográficos
Autores principales:	Troadec, Samuel, Blairvacq, Mélina, Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Berthou, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504225/ https://www.ncbi.nlm.nih.gov/pubmed/26184865 http://dx.doi.org/10.1186/s12929-015-0163-x

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