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SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation

Synapsins are key components of the presynaptic neurotransmitter release machinery. Their main role is to cluster synaptic vesicles (SVs) to each other and anchor them to the actin cytoskeleton to establish the reserve vesicle pool, and then release them in response to appropriate membrane depolariz...

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Detalles Bibliográficos
Autores principales: Tang, Leo T. -H., Craig, Tim J., Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504226/
https://www.ncbi.nlm.nih.gov/pubmed/26173895
http://dx.doi.org/10.1038/ncomms8728