Knockdown of the Inhibitor of Apoptosis BRUCE Sensitizes Resistant Breast Cancer Cells to Chemotherapeutic Agents

BACKGROUND AND OBJECTIVES: Management of patients with breast cancer often fails because of inherent or acquired resistance to chemotherapy. BRUCE (BIR repeat containing ubiquitin-conjugating enzyme) is a member of the inhibitor of apoptosis protein (IAP) family. It has various cellular functions in...

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Detalles Bibliográficos
Autores principales: Garrison, Jason B, Ge, Chunmin, Che, Lixiao, Pullum, Derek A, Peng, Guang, Khan, Sohaib, Ben-Jonathan, Nira, Wang, Jiang, Du, Chunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504245/
https://www.ncbi.nlm.nih.gov/pubmed/26191375
http://dx.doi.org/10.4172/1948-5956.1000335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504245/
https://www.ncbi.nlm.nih.gov/pubmed/26191375
http://dx.doi.org/10.4172/1948-5956.1000335

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