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Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy

Serum levels of the interferon (IFN)-stimulated chemokine CXCL10 are increased during chronic HCV infection and associate with outcome of IFN-based therapy. Elevated levels of NH2-terminal truncated CXCL10 (3-77aa), produced by DPP4 cleavage, negatively associate with spontaneous clearance of acute...

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Detalles Bibliográficos
Autores principales: Meissner, Eric G., Decalf, Jérémie, Casrouge, Armanda, Masur, Henry, Kottilil, Shyam, Albert, Matthew L., Duffy, Darragh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504464/
https://www.ncbi.nlm.nih.gov/pubmed/26181438
http://dx.doi.org/10.1371/journal.pone.0133236