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Indexing Arbitrary-Length k-Mers in Sequencing Reads

We propose a lightweight data structure for indexing and querying collections of NGS reads data in main memory. The data structure supports the interface proposed in the pioneering work by Philippe et al. for counting and locating k-mers in sequencing reads. Our solution, PgSA (pseudogenome suffix a...

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Detalles Bibliográficos
Autores principales: Kowalski, Tomasz, Grabowski, Szymon, Deorowicz, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504488/
https://www.ncbi.nlm.nih.gov/pubmed/26182400
http://dx.doi.org/10.1371/journal.pone.0133198