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Hydrophobic Gating of Ion Permeation in Magnesium Channel CorA

Ion channels catalyze ionic permeation across membranes via water-filled pores. To understand how changes in intracellular magnesium concentration regulate the influx of Mg(2+) into cells, we examine early events in the relaxation of Mg(2+) channel CorA toward its open state using massively-repeated...

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Detalles Bibliográficos
Autores principales: Neale, Chris, Chakrabarti, Nilmadhab, Pomorski, Pawel, Pai, Emil F., Pomès, Régis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504495/
https://www.ncbi.nlm.nih.gov/pubmed/26181442
http://dx.doi.org/10.1371/journal.pcbi.1004303