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Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIV(MAC)/SIV(SM)/HIV-2 Lineage Prior to Integration
HIV-2 and SIV(MAC) are AIDS-causing, zoonotic lentiviruses that jumped to humans and rhesus macaques, respectively, from SIV(SM)-bearing sooty mangabey monkeys. Cross-species transmission events such as these sometimes necessitate virus adaptation to species-specific, host restriction factors such a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504712/ https://www.ncbi.nlm.nih.gov/pubmed/26181333 http://dx.doi.org/10.1371/journal.ppat.1005050 |