Cargando…
Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIV(MAC)/SIV(SM)/HIV-2 Lineage Prior to Integration
HIV-2 and SIV(MAC) are AIDS-causing, zoonotic lentiviruses that jumped to humans and rhesus macaques, respectively, from SIV(SM)-bearing sooty mangabey monkeys. Cross-species transmission events such as these sometimes necessitate virus adaptation to species-specific, host restriction factors such a...
Autores principales: | Pizzato, Massimo, McCauley, Sean Matthew, Neagu, Martha R., Pertel, Thomas, Firrito, Claudia, Ziglio, Serena, Dauphin, Ann, Zufferey, Madeleine, Berthoux, Lionel, Luban, Jeremy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504712/ https://www.ncbi.nlm.nih.gov/pubmed/26181333 http://dx.doi.org/10.1371/journal.ppat.1005050 |
Ejemplares similares
-
Lv4, an activity that restricts nuclear entry of SIV(MAC)/SIV(SM) in human blood cells
por: Pizzato, Massimo, et al.
Publicado: (2013) -
TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
por: Ohainle, Molly, et al.
Publicado: (2020) -
Immunization with Single-Cycle SIV Significantly Reduces Viral Loads After an Intravenous Challenge with SIV(mac)239
por: Jia, Bin, et al.
Publicado: (2009) -
Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factors
por: Mamede, João I, et al.
Publicado: (2013) -
ADCC Develops Over Time during Persistent Infection with Live-Attenuated SIV and Is Associated with Complete Protection against SIV(mac)251 Challenge
por: Alpert, Michael D., et al.
Publicado: (2012)