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Genetic risk factors affecting mitochondrial function are associated with kidney disease in people with Type 1 diabetes

AIM: To evaluate the association with diabetic kidney disease of single nucleotide polymorphisms (SNPs) that may contribute to mitochondrial dysfunction. METHODS: The mitochondrial genome and 1039 nuclear genes that are integral to mitochondrial function were investigated using a case (n = 823 indiv...

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Detalles Bibliográficos
Autores principales: Swan, E J, Salem, R M, Sandholm, N, Tarnow, L, Rossing, P, Lajer, M, Groop, P H, Maxwell, A P, McKnight, A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504747/
https://www.ncbi.nlm.nih.gov/pubmed/25819010
http://dx.doi.org/10.1111/dme.12763