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Regulation and function of the caspase-1 in an inflammatory microenvironment

The inflammasome is a complex of proteins that plays a critical role in mounting an inflammatory response in reply to a harmful stimulus that compromises the homeostatic state of the tissue. The NLRP3 inflammasome, which is found in a wound-like environment, is comprised of three components: the NLR...

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Detalles Bibliográficos
Autores principales: Lee, Dai-Jen, Du, Fei, Chen, Shih-Wei, Nakasaki, Manando, Rana, Isha, Shih, Vincent F.S., Hoffmann, Alexander, Jamora, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504759/
https://www.ncbi.nlm.nih.gov/pubmed/25815426
http://dx.doi.org/10.1038/jid.2015.119