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Regulation and function of the caspase-1 in an inflammatory microenvironment
The inflammasome is a complex of proteins that plays a critical role in mounting an inflammatory response in reply to a harmful stimulus that compromises the homeostatic state of the tissue. The NLRP3 inflammasome, which is found in a wound-like environment, is comprised of three components: the NLR...
Autores principales: | Lee, Dai-Jen, Du, Fei, Chen, Shih-Wei, Nakasaki, Manando, Rana, Isha, Shih, Vincent F.S., Hoffmann, Alexander, Jamora, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504759/ https://www.ncbi.nlm.nih.gov/pubmed/25815426 http://dx.doi.org/10.1038/jid.2015.119 |
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