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TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus

TNF-like weak inducer of apoptosis (TWEAK, TNFSF12) and its sole receptor Fn14, belonging to the TNF ligand and receptor superfamilies respectively, are involved in cell survival and cytokine production. The role of TWEAK/Fn14 interactions in the pathogenesis of cutaneous lupus has not been explored...

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Detalles Bibliográficos
Autores principales: Doerner, Jessica, Wen, Jing, Xia, Yumin, Paz, Karin Blecher, Schairer, David, Wu, Lan, Chalmers, Samantha A., Izmirly, Peter, Michaelson, Jennifer S., Burkly, Linda C., Friedman, Adam, Putterman, Chaim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504782/
https://www.ncbi.nlm.nih.gov/pubmed/25826425
http://dx.doi.org/10.1038/jid.2015.124