Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches

OBJECTIVE: The ductular reaction (DR) involves mobilisation of reactive-appearing duct-like cells (RDC) along canals of Hering, and myofibroblastic (MF) differentiation of hepatic stellate cells (HSC) in the space of Disse. Perivascular cells in stem cell niches produce pleiotrophin (PTN) to inactiv...

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Detalles Bibliográficos
Autores principales: Michelotti, Gregory A, Tucker, Anikia, Swiderska-Syn, Marzena, Machado, Mariana Verdelho, Choi, Steve S, Kruger, Leandi, Soderblom, Erik, Thompson, J Will, Mayer-Salman, Meredith, Himburg, Heather A, Moylan, Cynthia A, Guy, Cynthia D, Garman, Katherine S, Premont, Richard T, Chute, John P, Diehl, Anna Mae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504836/
https://www.ncbi.nlm.nih.gov/pubmed/25596181
http://dx.doi.org/10.1136/gutjnl-2014-308176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504836/
https://www.ncbi.nlm.nih.gov/pubmed/25596181
http://dx.doi.org/10.1136/gutjnl-2014-308176

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