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Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation

The mouse artificial chromosome (MAC) has several advantages as a gene delivery vector, including stable episomal maintenance of the exogenous genetic material and the ability to carry large and/or multiple gene inserts including their regulatory elements. Previously, a MAC containing multi-integrat...

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Detalles Bibliográficos
Autores principales: Yoshimura, Yuki, Nakamura, Kazuomi, Endo, Takeshi, Kajitani, Naoyo, Kazuki, Kanako, Kazuki, Yasuhiro, Kugoh, Hiroyuki, Oshimura, Mitsuo, Ohbayashi, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504986/
https://www.ncbi.nlm.nih.gov/pubmed/26055730
http://dx.doi.org/10.1007/s11248-015-9884-6