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Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation
The mouse artificial chromosome (MAC) has several advantages as a gene delivery vector, including stable episomal maintenance of the exogenous genetic material and the ability to carry large and/or multiple gene inserts including their regulatory elements. Previously, a MAC containing multi-integrat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504986/ https://www.ncbi.nlm.nih.gov/pubmed/26055730 http://dx.doi.org/10.1007/s11248-015-9884-6 |