Cargando…

Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation

The mouse artificial chromosome (MAC) has several advantages as a gene delivery vector, including stable episomal maintenance of the exogenous genetic material and the ability to carry large and/or multiple gene inserts including their regulatory elements. Previously, a MAC containing multi-integrat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoshimura, Yuki, Nakamura, Kazuomi, Endo, Takeshi, Kajitani, Naoyo, Kazuki, Kanako, Kazuki, Yasuhiro, Kugoh, Hiroyuki, Oshimura, Mitsuo, Ohbayashi, Tetsuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2015
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504986/ https://www.ncbi.nlm.nih.gov/pubmed/26055730 http://dx.doi.org/10.1007/s11248-015-9884-6

Ejemplares similares

Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice
por: Abe, Satoshi, et al.
Publicado: (2021)

Transfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice
por: Shinohara, Takashi, et al.
Publicado: (2017)

Analysis of in vitro and in vivo metabolism of zidovudine and gemfibrozil in trans‐chromosomic mouse line expressing human UGT2 enzymes
por: Kobayashi, Kaoru, et al.
Publicado: (2022)

Multiple expression cassette exchange via TP901‐1, R4, and Bxb1 integrase systems on a mouse artificial chromosome
por: Tomimatsu, Kosuke, et al.
Publicado: (2017)

A kidney injury molecule‐1 (Kim‐1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells
por: Kokura, Kenji, et al.
Publicado: (2016)

A non-mosaic transchromosomic mouse model of Down syndrome carrying the long arm of human chromosome 21
por: Kazuki, Yasuhiro, et al.
Publicado: (2020)

Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas9
por: Honma, Kazuhisa, et al.
Publicado: (2018)

A Method for Producing Transgenic Cells Using a Multi-Integrase System on a Human Artificial Chromosome Vector
por: Yamaguchi, Shigeyuki, et al.
Publicado: (2011)

Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer
por: Katoh, Motonobu, et al.
Publicado: (2010)

Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism
por: Kazuki, Yasuhiro, et al.
Publicado: (2019)

Use of a Human Artificial Chromosome for Delivering Trophic Factors in a Rodent Model of Amyotrophic Lateral Sclerosis
por: Watanabe, Yasuhiro, et al.
Publicado: (2015)

A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges
por: Oshimura, Mitsuo, et al.
Publicado: (2015)

Full-length human dystrophin on human artificial chromosome compensates for mouse dystrophin deficiency in a Duchenne muscular dystrophy mouse model
por: Hiramuki, Yosuke, et al.
Publicado: (2023)

An efficient protein production system via gene amplification on a human artificial chromosome and the chromosome transfer to CHO cells
por: Ohira, Takahito, et al.
Publicado: (2019)

Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies
por: Kazuki, Yasuhiro, et al.
Publicado: (2014)

Thalidomide-induced limb abnormalities in a humanized CYP3A mouse model
por: Kazuki, Yasuhiro, et al.
Publicado: (2016)

Development of Caco-2 cells expressing four CYPs via a mammalian artificial chromosome
por: Ohta, Yumi, et al.
Publicado: (2020)

Modification of single-nucleotide polymorphism in a fully humanized CYP3A mouse by genome editing technology
por: Abe, Satoshi, et al.
Publicado: (2017)

Studies of Tumor Suppressor Genes via Chromosome Engineering
por: Kugoh, Hiroyuki, et al.
Publicado: (2015)

Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats
por: Kobayashi, Toshihiro, et al.
Publicado: (2021)

A luciferase complementation assay system using transferable mouse artificial chromosomes to monitor protein–protein interactions mediated by G protein-coupled receptors
por: Uno, Narumi, et al.
Publicado: (2018)

Panel of human cell lines with human/mouse artificial chromosomes
por: Uno, Narumi, et al.
Publicado: (2022)

Increased Frequencies of Gene and Chromosome Mutations after X‐Irradiation in Mouse Embryonal Carcinoma Cells Transfected with the bcl‐2 Gene
por: Taga, Masataka, et al.
Publicado: (2000)

Establishment and Characterization of a Transgenic Mouse Model for In Vivo Imaging of Bmp4 Expression in the Pancreas
por: Yasunaga, Mayu, et al.
Publicado: (2011)

Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse
por: Dunlevy, Louisa, et al.
Publicado: (2010)

Establishment of a novel hepatocyte model that expresses four cytochrome P450 genes stably via mammalian-derived artificial chromosome for pharmacokinetics and toxicity studies
por: Satoh, Daisuke, et al.
Publicado: (2017)

Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy
por: Kazuki, Yasuhiro, et al.
Publicado: (2009)

Engineering of human induced pluripotent stem cells via human artificial chromosome vectors for cell therapy and disease modeling
por: Kazuki, Yasuhiro, et al.
Publicado: (2020)

A Novel System for Simultaneous or Sequential Integration of Multiple Gene-Loading Vectors into a Defined Site of a Human Artificial Chromosome
por: Suzuki, Teruhiko, et al.
Publicado: (2014)

A Human Artificial Chromosome Recapitulates the Metabolism of Native Telomeres in Mammalian Cells
por: Wakai, Michihito, et al.
Publicado: (2014)

Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope Proteins
por: Suzuki, Teruhiko, et al.
Publicado: (2016)

CRISPR/Cas9-induced transgene insertion and telomere-associated truncation of a single human chromosome for chromosome engineering in CHO and A9 cells
por: Uno, Narumi, et al.
Publicado: (2017)

Subchromosomal Mapping of a Putative Transformation Suppressor Gene on Human Chromosome 1
por: Horikawa, Izumi, et al.
Publicado: (1995)

Dual-Color Fluorescence Imaging to Monitor CYP3A4 and CYP3A7 Expression in Human Hepatic Carcinoma HepG2 and HepaRG Cells
por: Tsuji, Saori, et al.
Publicado: (2014)

Chromosome Instability in mouse Embryonic Stem Cells
por: Gaztelumendi, Nerea, et al.
Publicado: (2014)

Comparison of survival rates in four inbred mouse strains under different housing conditions: effects of environmental enrichment
por: Kawakami, Kohei, et al.
Publicado: (2021)

Real‐time fluorometric evaluation of hepatoblast proliferation in vivo and in vitro using the expression of CYP3A7 coding for human fetus‐specific P450
por: Okuyama, Shota, et al.
Publicado: (2020)

Construction of Mouse A9 Clones Containing a Single Human Chromosome (X/Autosome Translocation) via Micro‐cell Fusion
por: Koi, Minoru, et al.
Publicado: (1989)

Construction of Mouse A9 Clones Containing a Single Human Chromosome Tagged with Neomycin‐resistance Gene via Microcell Fusion
por: Koi, Minoru, et al.
Publicado: (1989)

Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors
por: Hiratsuka, Masaharu, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_v6ss1e2elgemk93s9cvfse5dam