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Lessons from mouse chimaera experiments with a reiterated transgene marker: revised marker criteria and a review of chimaera markers

Recent reports of a new generation of ubiquitous transgenic chimaera markers prompted us to consider the criteria used to evaluate new chimaera markers and develop more objective assessment methods. To investigate this experimentally we used several series of fetal and adult chimaeras, carrying an o...

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Detalles Bibliográficos
Autores principales: Keighren, Margaret A., Flockhart, Jean, Hodson, Benjamin A., Shen, Guan-Yi, Birtley, James R., Notarnicola-Harwood, Antonio, West, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504987/
https://www.ncbi.nlm.nih.gov/pubmed/26048593
http://dx.doi.org/10.1007/s11248-015-9883-7