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In Vitro Antifungal Activity and Mode of Action of 2',4'-Dihydroxychalcone against Aspergillus fumigatus

2',4'-Dihydroxychalcone (2',4'-DHC) was identified from a heat shock protein 90 (Hsp90)-targeting library as a compound with Hsp90 inhibitory and antifungal effects. In the presence of 2',4'-DHC (8 µg/mL), radial growth of Aspergillus fumigatus was inhibited 20% compare...

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Detalles Bibliográficos
Autores principales: Seo, Young Ho, Kim, Sung-Su, Shin, Kwang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Mycology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505003/
https://www.ncbi.nlm.nih.gov/pubmed/26190922
http://dx.doi.org/10.5941/MYCO.2015.43.2.150