Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Class IIa histone deacetylases repress transcription of target genes. However, their mechanism of action is poorly understood because they exhibit very low levels of deacetylase activity. The class IIa HDACs are associated with the SMRT/NCoR repression complexes and this may, at least in part, accou...

Descripción completa

Detalles Bibliográficos
Autores principales: Hudson, Gregg M., Watson, Peter J., Fairall, Louise, Jamieson, Andrew G., Schwabe, John W. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Gene Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505066/
https://www.ncbi.nlm.nih.gov/pubmed/26055705
http://dx.doi.org/10.1074/jbc.M115.661058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505066/
https://www.ncbi.nlm.nih.gov/pubmed/26055705
http://dx.doi.org/10.1074/jbc.M115.661058

Ejemplares similares