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Studying GPCR/cAMP pharmacology from the perspective of cellular structure

Signal transduction via G-protein coupled receptors (GPCRs) relies upon the production of cAMP and other signaling cascades. A given receptor and agonist pair, produce multiple effects upon cellular physiology which can be opposite in different cell types. The production of variable cellular effects...

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Detalles Bibliográficos
Autores principales: Wright, Peter T., Schobesberger, Sophie, Gorelik, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505077/
https://www.ncbi.nlm.nih.gov/pubmed/26236239
http://dx.doi.org/10.3389/fphar.2015.00148