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Azobenzene-based inhibitors of human carbonic anhydrase II

Aryl sulfonamides are a widely used drug class for the inhibition of carbonic anhydrases. In the context of our program of photochromic pharmacophores we were interested in the exploration of azobenzene-containing sulfonamides to block the catalytic activity of human carbonic anhydrase II (hCAII). H...

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Detalles Bibliográficos
Autores principales: Runtsch, Leander Simon, Barber, David Michael, Mayer, Peter, Groll, Michael, Trauner, Dirk, Broichhagen, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505086/
https://www.ncbi.nlm.nih.gov/pubmed/26199669
http://dx.doi.org/10.3762/bjoc.11.127