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Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging

The aging process of skin has been investigated recently with respect to mitochondrial function and oxidative stress. We have here observed striking phenotypic and clinical similarity between skin aging and recessive dystrophic Epidermolysis bullosa (RDEB), which is caused by recessive mutations in...

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Detalles Bibliográficos
Autores principales: Breitenbach, Jenny S., Rinnerthaler, Mark, Trost, Andrea, Weber, Manuela, Klausegger, Alfred, Gruber, Christina, Bruckner, Daniela, Reitsamer, Herbert A., Bauer, Johann W., Breitenbach, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505166/
https://www.ncbi.nlm.nih.gov/pubmed/26143532