Premature aging of the hippocampal neurogenic niche in adult Bmal1‐ deficient mice

Hippocampal neurogenesis undergoes dramatic age‐related changes. Mice with targeted deletion of the clock gene Bmal1 (Bmal1(‐/‐)) show disrupted regulation of reactive oxygen species homeostasis, accelerated aging, neurodegeneration and cognitive deficits. As proliferation of neuronal progenitor/pre...

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Detalles Bibliográficos
Autores principales: Ali, Amira A. H., Schwarz‐Herzke, Beryl, Stahr, Anna, Prozorovski, Timour, Aktas, Orhan, von Gall, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505169/
https://www.ncbi.nlm.nih.gov/pubmed/26142744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505169/
https://www.ncbi.nlm.nih.gov/pubmed/26142744

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