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Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.0(2,6)]undeca-3,11-dione and its congeners via ring-closing metathesis
We have developed a simple methodology to transform cis-syn-cis-triquinane derivative 2 into the diindole based macrocycle 6 involving Fischer indolization and ring-closing metathesis (RCM). Various spiro-polyquinane derivatives have been assembled via RCM as a key step.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505178/ https://www.ncbi.nlm.nih.gov/pubmed/26199668 http://dx.doi.org/10.3762/bjoc.11.126 |