Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus

The echinocandin antifungal drug caspofungin at high concentrations reverses the growth inhibition of Aspergillus fumigatus, a phenomenon known as the “paradoxical effect,” which is not consistently observed with other echinocandins (micafungin and anidulafungin). Previous studies of A. fumigatus re...

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Detalles Bibliográficos
Autores principales: Juvvadi, Praveen R., Muñoz, Alberto, Lamoth, Frédéric, Soderblom, Erik J., Moseley, M. Arthur, Read, Nick D., Steinbach, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505252/
https://www.ncbi.nlm.nih.gov/pubmed/26055379
http://dx.doi.org/10.1128/AAC.00263-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505252/
https://www.ncbi.nlm.nih.gov/pubmed/26055379
http://dx.doi.org/10.1128/AAC.00263-15

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