MAD1L1 Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer

The spindle assembly checkpoint (SAC) has been established as an important mechanism of driving aneuploidy, which occurs at a high frequency in the colorectal tumorigenesis. Two important components of SAC are MAD1L1 and MAD2L1, which function together in an interactive manner to initiate the checkp...

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Detalles Bibliográficos
Autores principales: Zhong, Rong, Chen, Xiaohua, Chen, Xueqin, Zhu, Beibei, Lou, Jiao, Li, Jiaoyuan, Shen, Na, Yang, Yang, Gong, Yajie, Zhu, Ying, Yuan, Jing, Xia, Xiaoping, Miao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505328/
https://www.ncbi.nlm.nih.gov/pubmed/26183163
http://dx.doi.org/10.1038/srep12202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505328/
https://www.ncbi.nlm.nih.gov/pubmed/26183163
http://dx.doi.org/10.1038/srep12202

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