Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons

During nervous system development, commissural axons cross the midline despite the presence of repellant ligands. In Drosophila, commissural axons avoid premature responsiveness to the midline repellant Slit by expressing the endosomal sorting receptor Commissureless, which reduces surface expressio...

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Detalles Bibliográficos
Autores principales: Evans, Timothy A, Santiago, Celine, Arbeille, Elise, Bashaw, Greg J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505356/
https://www.ncbi.nlm.nih.gov/pubmed/26186094
http://dx.doi.org/10.7554/eLife.08407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505356/
https://www.ncbi.nlm.nih.gov/pubmed/26186094
http://dx.doi.org/10.7554/eLife.08407

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