Cargando…
Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
During nervous system development, commissural axons cross the midline despite the presence of repellant ligands. In Drosophila, commissural axons avoid premature responsiveness to the midline repellant Slit by expressing the endosomal sorting receptor Commissureless, which reduces surface expressio...
Autores principales: | Evans, Timothy A, Santiago, Celine, Arbeille, Elise, Bashaw, Greg J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505356/ https://www.ncbi.nlm.nih.gov/pubmed/26186094 http://dx.doi.org/10.7554/eLife.08407 |
Ejemplares similares
-
Slit-Dependent Endocytic Trafficking of the Robo Receptor Is Required for Son of Sevenless Recruitment and Midline Axon Repulsion
por: Chance, Rebecca K., et al.
Publicado: (2015) -
Beyond Axon Guidance: Roles of Slit-Robo Signaling in Neocortical Formation
por: Gonda, Yuko, et al.
Publicado: (2020) -
Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion
por: Chaudhari, Karina, et al.
Publicado: (2021) -
Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2
por: Johnson, Verity, et al.
Publicado: (2019) -
Cables1 links Slit/Robo and Wnt/Frizzled signaling in commissural axon guidance
por: Zuñiga, Nikole R., et al.
Publicado: (2023)