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Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets
Dendritic cells (DCs) have the unique ability to pick up dead cells carrying antigens in tissue and migrate to the lymph nodes where they can cross-present cell-associated antigens by MHC class I to CD8(+) T cells. There is strong in vivo evidence that the mouse XCR1(+) DCs subset acts as a key play...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505393/ https://www.ncbi.nlm.nih.gov/pubmed/26236315 http://dx.doi.org/10.3389/fimmu.2015.00363 |