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Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets

Dendritic cells (DCs) have the unique ability to pick up dead cells carrying antigens in tissue and migrate to the lymph nodes where they can cross-present cell-associated antigens by MHC class I to CD8(+) T cells. There is strong in vivo evidence that the mouse XCR1(+) DCs subset acts as a key play...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Martínez, Enric, Planès, Remi, Anselmi, Giorgio, Reynolds, Matthew, Menezes, Shinelle, Adiko, Aimé Cézaire, Saveanu, Loredana, Guermonprez, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505393/
https://www.ncbi.nlm.nih.gov/pubmed/26236315
http://dx.doi.org/10.3389/fimmu.2015.00363