A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2

Blood dendritic cell antigen 2 (BDCA-2; also designated CLEC4C or CD303) is uniquely expressed on plasmacytoid dendritic cells. Stimulation of BDCA-2 with antibodies leads to an anti-inflammatory response in these cells, but the natural ligands for the receptor are not known. The C-type carbohydrate...

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Detalles Bibliográficos
Autores principales: Jégouzo, Sabine A. F., Feinberg, Hadar, Dungarwalla, Tabassum, Drickamer, Kurt, Weis, William I., Taylor, Maureen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505424/
https://www.ncbi.nlm.nih.gov/pubmed/25995448
http://dx.doi.org/10.1074/jbc.M115.660613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505424/
https://www.ncbi.nlm.nih.gov/pubmed/25995448
http://dx.doi.org/10.1074/jbc.M115.660613

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