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Distinct Agonist Regulation of Muscarinic Acetylcholine M(2)-M(3) Heteromers and Their Corresponding Homomers

Each subtype of the muscarinic receptor family of G protein-coupled receptors is activated by similar concentrations of the neurotransmitter acetylcholine or closely related synthetic analogs such as carbachol. However, pharmacological selectivity can be generated by the introduction of a pair of mu...

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Detalles Bibliográficos
Autores principales: Aslanoglou, Despoina, Alvarez-Curto, Elisa, Marsango, Sara, Milligan, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505543/
https://www.ncbi.nlm.nih.gov/pubmed/25918156
http://dx.doi.org/10.1074/jbc.M115.649079