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Yeast m(6)A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment

Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the finding of FTO’s (Fat Mass Obesity) N6-methyl-adenosine (m(6)A) deaminase activity, thus suggesting a link between obesity-associated diseases and the presence of m(6)A in...

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Detalles Bibliográficos
Autores principales: Bodi, Zsuzsanna, Bottley, Andrew, Archer, Nathan, May, Sean T., Fray, Rupert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505848/
https://www.ncbi.nlm.nih.gov/pubmed/26186436
http://dx.doi.org/10.1371/journal.pone.0132090