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A Model for Osteonecrosis of the Jaw with Zoledronate Treatment following Repeated Major Trauma
This study aims to develop a reproducible rat model for post-traumatic bisphosphonate-related osteonecrosis of the jaw (BRONJ). In our previous studies using dental extraction as an inducing factor, only 30% - 60% of zoledronate-treated animals fulfilled the definition of clinical BRONJ. We modified...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505856/ https://www.ncbi.nlm.nih.gov/pubmed/26186665 http://dx.doi.org/10.1371/journal.pone.0132520 |