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Novel Phosphotidylinositol 4,5-Bisphosphate Binding Sites on Focal Adhesion Kinase
Focal adhesion kinase (FAK) is a protein tyrosine kinase that is ubiquitously expressed, recruited to focal adhesions, and engages in a variety of cellular signaling pathways. Diverse cellular responses, such as cell migration, proliferation, and survival, are regulated by FAK. Prior to activation,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505859/ https://www.ncbi.nlm.nih.gov/pubmed/26186725 http://dx.doi.org/10.1371/journal.pone.0132833 |