Discs Large Homolog 1 Splice Variants Regulate p38 –Dependent and –Independent Effector Functions in CD8+ T Cells

Functionally diverse CD8+ T cells develop in response to antigenic stimulation with differing capacities to couple TCR engagement to downstream signals and functions. However, mechanisms of diversifying TCR signaling are largely uncharacterized. Here we identified two alternative splice variants of...

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Detalles Bibliográficos
Autores principales: Silva, Oscar, Crocetti, Jillian, Humphries, Lisa A., Burkhardt, Janis K., Miceli, M. Carrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505885/
https://www.ncbi.nlm.nih.gov/pubmed/26186728
http://dx.doi.org/10.1371/journal.pone.0133353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505885/
https://www.ncbi.nlm.nih.gov/pubmed/26186728
http://dx.doi.org/10.1371/journal.pone.0133353

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