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Discs Large Homolog 1 Splice Variants Regulate p38 –Dependent and –Independent Effector Functions in CD8+ T Cells
Functionally diverse CD8+ T cells develop in response to antigenic stimulation with differing capacities to couple TCR engagement to downstream signals and functions. However, mechanisms of diversifying TCR signaling are largely uncharacterized. Here we identified two alternative splice variants of...
Autores principales: | Silva, Oscar, Crocetti, Jillian, Humphries, Lisa A., Burkhardt, Janis K., Miceli, M. Carrie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505885/ https://www.ncbi.nlm.nih.gov/pubmed/26186728 http://dx.doi.org/10.1371/journal.pone.0133353 |
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