Bioactivity Studies of β-Lactam Derived Polycyclic Fused Pyrroli-Dine/Pyrrolizidine Derivatives in Dentistry: In Vitro, In Vivo and In Silico Studies

The antibacterial activity of β-lactam derived polycyclic fused pyrrolidine/pyrrolizidine derivatives synthesized by 1, 3-dipolar cycloaddition reaction was evaluated against microbes involved in dental infection. Fifteen compounds were screened; among them compound 3 showed efficient antibacterial...

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Detalles Bibliográficos
Autores principales: Meiyazhagan, Gowri, Raju, Rajesh, Winfred, Sofi Beaula, Mannivanan, Bhavani, Bhoopalan, Hemadev, Shankar, Venkatesh, Sekar, Sathiya, Venkatachalam, Deepa Parvathi, Pitani, Ravishankar, Nagendrababu, Venkateshbabu, Thaiman, Malini, Devivanayagam, Kandaswamy, Jayaraman, Jeyakanthan, Ragavachary, Raghunathan, Venkatraman, Ganesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505899/
https://www.ncbi.nlm.nih.gov/pubmed/26185985
http://dx.doi.org/10.1371/journal.pone.0131433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505899/
https://www.ncbi.nlm.nih.gov/pubmed/26185985
http://dx.doi.org/10.1371/journal.pone.0131433

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