Cargando…

ELISA-Based Detection System for Protein S K196E Mutation, a Genetic Risk Factor for Venous Thromboembolism

Protein S (PS) acts as a cofactor for activated protein C in the plasma anticoagulant system. PS Lys196-to-Glu (K196E) mutation is a genetic risk factor for venous thromboembolism in Japanese individuals. Because of the substantial overlap in PS anticoagulant activity between KK (wild-type) and KE (...

Descripción completa

Detalles Bibliográficos
Autores principales: Maruyama, Keiko, Akiyama, Masashi, Kokame, Koichi, Sekiya, Akiko, Morishita, Eriko, Miyata, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505939/
https://www.ncbi.nlm.nih.gov/pubmed/26186226
http://dx.doi.org/10.1371/journal.pone.0133196