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ELISA-Based Detection System for Protein S K196E Mutation, a Genetic Risk Factor for Venous Thromboembolism

Protein S (PS) acts as a cofactor for activated protein C in the plasma anticoagulant system. PS Lys196-to-Glu (K196E) mutation is a genetic risk factor for venous thromboembolism in Japanese individuals. Because of the substantial overlap in PS anticoagulant activity between KK (wild-type) and KE (...

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Detalles Bibliográficos
Autores principales:	Maruyama, Keiko, Akiyama, Masashi, Kokame, Koichi, Sekiya, Akiko, Morishita, Eriko, Miyata, Toshiyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505939/ https://www.ncbi.nlm.nih.gov/pubmed/26186226 http://dx.doi.org/10.1371/journal.pone.0133196

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