Vimentin Phosphorylation Underlies Myofibroblast Sensitivity to Withaferin A In Vitro and during Corneal Fibrosis

Vimentin is a newly recognized target for corneal fibrosis. Using primary rabbit corneal fibroblasts and myofibroblasts we show that myofibroblasts, unlike fibroblasts, display impaired cell spreading and cell polarization, which is associated with increased levels of soluble serine-38 phosphorylate...

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Detalles Bibliográficos
Autores principales: Bargagna-Mohan, Paola, Lei, Ling, Thompson, Alexis, Shaw, Camille, Kasahara, Kousuke, Inagaki, Masaki, Mohan, Royce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506086/
https://www.ncbi.nlm.nih.gov/pubmed/26186445
http://dx.doi.org/10.1371/journal.pone.0133399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506086/
https://www.ncbi.nlm.nih.gov/pubmed/26186445
http://dx.doi.org/10.1371/journal.pone.0133399

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